MICE COLONIZED WITH THE DEFINED MICROBIAL COMMUNITY OMM19.1 ARE SUSCEPTIBLE TO CLOSTRIDIOIDES DIFFICILE INFECTION WITHOUT PRIOR ANTIBIOTIC TREATMENT

Mice colonized with the defined microbial community OMM19.1 are susceptible to Clostridioides difficile infection without prior antibiotic treatment

ABSTRACT Diverse gut microorganisms present in humans and mice are essential for the prevention of microbial pathogen colonization.However, antibiotic-induced dysbiosis of the gut microbiome reduces microbial diversity and allows Clostridioides difficile (C.difficile) to colonize the intestine.The Oligo-Mouse-Microbiota 19.1 (OMM19.1) is a syntheti

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Clinical Outcome of a New Surgical Technique for the Treatment of Peri-Implant Dehiscence in the Esthetic Area. A Case Report

This study describes the clinical and esthetic outcome of n apical surgical treatment on peri-implant soft tissue dehiscence in an implant with a poor prognosis in the esthetic area.The patient presented a compromised situation of clinical attachment loss both in the 1.2 implant and in the Middle Console Overlay adjacent teeth.A biphasic approach c

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Efficacy and Safety of Herbal Medicine Bojungikki-Tang in Combination with Pembrolizumab versus Pembrolizumab Monotherapy for Stage IV Non-Small Cell Lung Cancer: Study Protocol for a Randomized, Open-Label, Double-Arm, Multicenter Trial

Background: Non-small cell lung cancer (NSCLC) exhibits low survival rates.Although immune checkpoint inhibitors (ICIs) have become first-line treatment for NSCLC, their limited response to ICI monotherapy has led to exploration of combination treatments.However, the high incidence of treatment-related adverse events associated with conventional dr

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Evaluating diagnostic utility of PAS stained skin scrape cytology smear in clinically suspected superficial cutaneous mycoses: A simple yet unpracticed technique

Background and Objectives: For fungal dermatitis, a wet Potassium Hydroxide (KOH) preparation of the skin scrapings forms the routine practice for diagnosis.This study was carried out to determine the diagnostic accuracy and to evaluate the value-added information of PAS-stained scrape cytology smear in evaluating the presence of fungal elements.Me

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